KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASAL2
All Species:
30.3
Human Site:
T508
Identified Species:
74.07
UniProt:
Q9UJF2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJF2
NP_004832.1
1139
128558
T508
D
R
T
S
R
T
L
T
L
I
A
K
V
I
Q
Chimpanzee
Pan troglodytes
XP_001154057
1139
128497
T508
D
R
T
S
R
T
L
T
L
I
A
K
V
I
Q
Rhesus Macaque
Macaca mulatta
XP_001109824
1284
140910
T565
E
Q
T
S
R
T
L
T
L
I
A
K
V
I
Q
Dog
Lupus familis
XP_850226
1139
128586
T508
D
R
T
S
R
T
L
T
L
I
A
K
V
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHC7
1189
131708
T552
D
R
T
A
R
T
L
T
L
I
A
K
V
T
Q
Rat
Rattus norvegicus
Q6P730
996
109986
I418
T
A
G
F
E
G
Y
I
D
L
G
R
E
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515620
1407
158451
T772
D
R
T
S
R
T
L
T
L
I
A
K
V
I
Q
Chicken
Gallus gallus
XP_426625
1279
143612
T648
D
R
T
S
R
T
L
T
L
I
A
K
V
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001332688
1136
127484
E514
G
M
T
R
F
L
L
E
I
S
N
L
E
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T498
1580
173511
T657
A
R
A
T
R
N
L
T
L
V
A
K
T
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
45.4
98.4
N.A.
57.4
50.9
N.A.
69.7
82.4
N.A.
74
N.A.
27.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
60.9
99.3
N.A.
71.4
64.1
N.A.
74.9
85.6
N.A.
83.4
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
86.6
0
N.A.
100
100
N.A.
13.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
100
100
N.A.
20
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
0
0
0
0
80
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
0
10
0
0
0
0
20
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
70
0
0
0
60
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% K
% Leu:
0
0
0
0
0
10
90
0
80
10
0
10
0
20
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
80
% Q
% Arg:
0
70
0
10
80
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
60
0
0
0
0
0
10
0
0
0
0
10
% S
% Thr:
10
0
80
10
0
70
0
80
0
0
0
0
10
20
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _